Musk ketone( —— )

Catalog No. M20360 CAS No. 81-14-1

Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Musk ketone
Note

Research use only, not for human use.
Brief Description

Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.
Description

Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.
In Vitro

Apoptosis Analysis Cell Line:AGS, HGC-27 Concentration:4.2 μM for AGS, 10.06 μM for HGC-27 Incubation Time:48 h Result:Increased ratio of Cle-caspase 3 to caspase 3 protein level.Induced cell apoptosis, detected by PI/Annexin V staining;
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

81-14-1
Formula Weight

294.3
Molecular Formula

C14H18N2O5
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 125 mg/mL (424.74 mM)
SMILES

CC(=O)c1c(C)c(c(c(c1C)[N+]([O-])=O)C(C)(C)C)[N+]([O-])=O
Chemical Name

4'-tert-Butyl-2'6'-dimethyl-3'5'-dinitroacetophenone

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Xu L Cao Y . Native musk and synthetic musk ketone strongly induced the growth repression and the apoptosis of cancer cells[J]. BMC Complementary and Alternative Medicine 2016 16(1).

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