Musk ketone

CAS No. 81-14-1

Musk ketone( —— )

Catalog No. M20360 CAS No. 81-14-1

Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Musk ketone
  • Note
    Research use only, not for human use.
  • Brief Description
    Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.
  • Description
    Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.
  • In Vitro
    Apoptosis Analysis Cell Line:AGS, HGC-27 Concentration:4.2 μM for AGS, 10.06 μM for HGC-27 Incubation Time:48 h Result:Increased ratio of Cle-caspase 3 to caspase 3 protein level.Induced cell apoptosis, detected by PI/Annexin V staining;
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    81-14-1
  • Formula Weight
    294.3
  • Molecular Formula
    C14H18N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 125 mg/mL (424.74 mM)
  • SMILES
    CC(=O)c1c(C)c(c(c(c1C)[N+]([O-])=O)C(C)(C)C)[N+]([O-])=O
  • Chemical Name
    4'-tert-Butyl-2'6'-dimethyl-3'5'-dinitroacetophenone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xu L Cao Y . Native musk and synthetic musk ketone strongly induced the growth repression and the apoptosis of cancer cells[J]. BMC Complementary and Alternative Medicine 2016 16(1).
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